Erik Spoelstra has said Bosh won’t play in Games 3 or 4, but his word isn’t binding.
Without Bosh, the Heat are obviously still formidable. Shane Battier spaces the floor a little more, LeBron James and Dwyane Wade both get a few more touches and JoDonis Anthlem does a good job with the dirty work.
But the Heat are a better team with Bosh. He has more length to contend with Kevin Garnett (though Garnett normally seems to handle Bosh, Bosh got the best of him last postseason) and his presence would give the Heat a third player who can make plays (and fourth if you count Mario Chalmers, who played out of his mind in Game 2).